Saturday, April 27, 2019

Stem cells and aging brain

Aging is part of life, but as our body ages, our brains will age. Just as the aging body may be full of diseases such as arthritis, cataracts, cardiovascular diseases and osteoporosis, the aging brain may also be sick. Age-related diseases that affect the brain usually accumulate under the general term "neurodegenerative". Diseases such as Huntington's disease, Alzheimer's disease and Parkinson's disease are some of the more well-known diseases that fall under this terminology.

Let us first understand the meaning of the term "neurological degeneration". Actually included. The Oxford Dictionary defines neurodegeneration as "degeneration of the nervous system, especially the degradation of brain neurons." According to the EU Joint Program - Neurodegenerative Diseases Research [JPND], the human nervous system nervous system enterprise. If they suffer damage, they will not be able to repair, replace or copy themselves. This inability leads to neurodegenerative diseases.

Previously, neurodegenerative diseases were considered incurable. However, with the tremendous advances in medical science in recent years, scientists have been able to design procedures that help individuals with neurodegenerative diseases. Stem cell therapy is one of the most advanced programs that have recently shown positive results.

These cells are mother cells or host cells that are capable of differentiating into other types of specialized cells through the mitotic process. They can repair internal tissue damage by developing cells that have special functions such as blood cells or brain cells. They also have the ability to self-renew.

The use of these types of cells to treat medical conditions and diseases is known as stem cell therapy. Stem cell transplantation is the most common method used in this cell therapy. In the case of brain degeneration, stem cells are transplanted into a patient. These cells then become progenitors that function in the brain to maintain neuronal function. Animal models of diseases such as amyotrophic lateral sclerosis, Parkinson's disease and multiple sclerosis have been studied, and these diseases provide optimistic results.

At a seminar organized by EuroStemCell, Dr. Magdalena Götz, HelmholtzZentrum München talked about the radial glial cells present in neural stem cells and described them as "they look like glia, they smell like glia, but they actually It is a neural stem cell. "She further explained the development of brain cells and the possibility of guiding neural stem cells to localize and repair damaged parts of the brain, as well as regenerating neurons.

Stem cell research is the future of neurology. With several clinical studies year after year, the use of cells in this therapy has been expanding in the treatment of neurological disorders. In India, the guidelines for clinical research developed by the Indian Medical Research Council [ICMR] have been thoroughly reformed, leading to in-depth research in the field of stem cell therapy.





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