Iodine has long been used as an antibacterial agent and a skin disinfectant. It was discovered in 1811 and was widely popular during the American Civil War, where it was widely used to treat soldiers' wounds. In its original form, iodine causes pain and irritation when applied to a wound, which has been shown to impair the function of cells involved in wound healing, and also has unfortunate side effects of skin discoloration.
Since the late 1940s, newer, safer and less painful iodine formulations have emerged in the form of iodophors. These products release a sustained low level of iodine that binds to proteins, fatty acids and nucleotides. These products have a broad spectrum of activity against bacteria, mycobacteria, fungi and protozoa.
Cadexomer iodine
Cadexomer iodine is a sustained release antimicrobial that has the ability to absorb excess wound exudate while maintaining a sustained iodine level in the wound bed. Cadexomer iodine can be used as a dressing and ointment. In the study, it has been shown to be effective in reducing the number of MRSA [methicillin-resistant Staphylococcus aureus] and Pseudomonas aeruginosa. It is estimated that 1 gram of Cadexomer iodine can absorb up to 7 ml of liquid. When iodine is absorbed, iodine is slowly released, which helps reduce bacterial load while clearing the wound. It requires moisture to be activated. Unlike povidone-iodine dressings that release iodine immediately after application, sustained release of iodine from the calcium protein iodine dressing does not cause cytotoxic effects.
Potential contraindications
Studies have shown that cadexomer iodine is effective in curing chronic ulcers; however, one of the serious potential side effects of using iodine to treat wounds is the possibility of absorbing iodine. Therefore, patients who have been using the therapy for a long time should monitor thyroid function. In addition, iodine may interact negatively with lithium and should be used with caution in patients who use lithium at the same time. Iodine should not be used with preservatives such as mercury, such as mercury red.
Given the increasing focus on the increase in antibiotic-resistant organisms, cadexomer iodine is an effective alternative to treating chronic wounds. Although iodine has been used for more than 150 years, there are few reports on iodine resistance. Cadexomer iodine can be safely used in most patients [provided they are not sensitive to iodine itself] and provides good coverage for bacteria, mycobacteria, fungi and protozoa, as well as for MRSA.
Orignal From: Application of iodine in wound care
No comments:
Post a Comment